Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
10 papers
Recent·Most cited
C. Fenwick, P. Turelli, Y. Duhoo, K. Lau, C. Herate, R. Marlin, M. Lamrayah, J. Campos, L. Leuenberger, A. Farina, c. raclot, V. Genet, F. Fiscalini, J. Cesborn, L. Perez, , G. Pantaleo
bioRxiv · Jul 18, 2023 · PreprintMicrobiology
C. Fenwick, P. Turelli, D. Ni, L. Perez, K. Lau, E. Lana, C. Pellaton, C. Raclot, L. Esteves-Leuenberger, J. Campos, A. Farina, F. Fiscalini, C. Herate, R. Marlin, R. Abdelnabi, , G. Pantaleo
This paper identifies a potent human monoclonal antibody, P2G3, that neutralizes multiple SARS-CoV-2 variants including Omicron, and demonstrates its protective efficacy in a monkey model.
bioRxiv · Mar 18, 2022 · PreprintImmunology
C. S.-Y. Foo, R. Abdelnabi, L. Vangeel, S. De Jonghe, D. Jochmans, B. Weynand, J. Neyts
This study shows that Ivermectin does not reduce SARS-CoV-2 lung viral load or improve lung pathology in Syrian hamsters and does not enhance Molnupiravir's effect.
bioRxiv · Feb 22, 2022Microbiology
R. Abdelnabi, C. S.-Y. Foo, X. Zhang, V. Lemmens, P. Maes, B. Slechten, J. Raymenants, E. Andre, B. Weynand, K. Dallmeier, J. Neyts
This study shows that the omicron SARS-CoV-2 variant infects Syrian hamsters with significantly lower viral loads in the lungs compared to the D614G strain, with no detectable infectious virus.
bioRxiv · Dec 24, 2021Microbiology
M. Imbrechts, W. Maes, L. Ampofo, N. Van den Berghe, B. Calcoen, D. Van Looveren, S. Noppen, K. Hollevoet, T. Vercruysse, X. Zhang, R. Abdelnabi, C. S.-Y. Foo, H. J. Thibaut, D. Jochmans, K. Ven, , N. Geukens
The paper identifies potent anti-SARS-CoV-2 mAbs that cure infection in hamsters and demonstrates gene-based delivery for in vivo protection against variants.
bioRxiv · Nov 25, 2021Immunology
R. Abdelnabi, C. S.-Y. Foo, D. Jochmans, L. Vangeel, S. De Jonghe, P. Augustijns, R. Mols, B. Weynand, T. Wattanakul, R. Hoglund, J. Tarning, C. Mowbray, P. Sjo, F. Escudie, I. Scandale, , J. Neyts
PF-07321332, an oral protease inhibitor, effectively protects Syrian hamsters against SARS-CoV-2 variants of concern, including beta and delta, by preventing infection and transmission.
bioRxiv · Nov 4, 2021Microbiology
D. Pinto, M. M. Sauer, N. Czudnochowski, J. S. Low, M. A. Tortorici, M. P. Housley, J. Noack, A. C. Walls, J. E. Bowen, B. Guarino, L. E. Rosen, J. di Iulio, J. Jerak, H. Kaiser, S. Islam, , Lanzave
This paper identifies a human antibody that broadly neutralizes betacoronaviruses by targeting the stem helix, showing protection against SARS-CoV-2 and potential for vaccine design.
bioRxiv · May 9, 2021 · PreprintImmunology
M. A. Tortorici, N. Czudnochowski, T. N. Starr, R. Marzi, A. C. Walls, F. Zatta, J. E. Bowen, S. Jaconi, J. di Iulio, Z. Wang, A. De Marco, S. Zepeda, D. Pinto, Z. Liu, M. Beltramello, , J. Bloom
This paper identifies a human monoclonal antibody that broadly neutralizes SARS-CoV-2 variants and zoonotic sarbecoviruses by targeting a conserved epitope on the spike protein.
bioRxiv · Apr 7, 2021 · PreprintImmunology
R. Abdelnabi, R. Boudewijns, C. S.-Y. Foo, L. Seldeslachts, L. Sanchez-Felipe, X. Zhang, L. Delang, P. Maes, S. J. F. Kaptein, B. Weynand, G. Vande Velde, J. Neyts, K. Dallmeier
This study compares the infectivity and pathogenicity of SARS-CoV-2 variants B.1.1.7 and B.1.351 to early 2020 strains in Syrian hamsters, finding similar disease outcomes but stronger proinflammatory cytokine elevation in B.1.1.7 infections.
bioRxiv · Feb 26, 2021Microbiology
J. Piton, A. Vocat, A. Lupien, C. S.-Y. Foo, O. Riabova, V. Makarov, S. T. Cole
The paper designs and characterizes sulfonyl-piperazine benzothiazinone inhibitors of DprE1 from M. tuberculosis, finding they have improved solubility but lower activity than MCZ.
bioRxiv · Apr 10, 2018Pharmacology & Toxicology