S. Noppen

C-terminal truncation of CXCL10 attenuates inflammatory activity but retains angiostatic properties

This study shows that truncating the C-terminus of CXCL10 reduces its inflammatory activity but maintains its anti-angiogenic effects.

Cellular electrical impedance to profile SARS-CoV-2 fusion inhibitors and to assess the fusogenic potential of spike mutants

This paper demonstrates the use of cellular electrical impedance to monitor SARS-CoV-2 spike-mediated cell-cell fusion and assess fusion inhibitors and spike mutants.

Carbohydrate-Binding Protein from Stinging Nettle as Fusion Inhibitor for SARS-CoV-2 Variants of Concern

This paper shows that UDA, a protein from stinging nettle, inhibits SARS-CoV-2 and its variants by blocking viral entry and fusion, with nanomolar potency.

SARS-CoV-2 Permissive Glioblastoma Cell Line for High Throughput Antiviral Screening

This paper develops a SARS-CoV-2 permissive glioblastoma cell line for high-throughput antiviral screening, showing it supports viral replication and provides reliable IC50 values for antivirals.

Potent neutralizing anti-SARS-CoV-2 human antibodies cure infection with SARS-CoV-2 variants in hamster model

The paper identifies potent anti-SARS-CoV-2 mAbs that cure infection in hamsters and demonstrates gene-based delivery for in vivo protection against variants.