BET-independent MLV integration is retargeted in vivo and selects distinct genomic elements for lymphomagenesis
I. Nombela, M. Michiels, D. Van Looveren, L. Marcelis, S. el Ashkar, S. Van Belle, A. Bruggemans, T. Tousseyn, J. Schwaller, F. Christ, R. Gijsbers, J. De Rijck, Z. Debyser
This study compares BET-dependent and -independent MLV integration in mice, finding that BET proteins influence integration site selection but not tumorigenesis.
bioRxiv · Feb 23, 2022 · PreprintMicrobiology