Oncogenic memory underlying minimal residual disease in breast cancer
K. R. Shechter, E. Kafkia, K. Zirngibl, S. Gawrzak, A. Alladin, D. Machado, C. Luechtenborg, D. C. Sevin, B. Bruegger, K. R. Patil, M. Jechlinger
This study identifies metabolic features of minimal residual disease (MRD) cells in breast cancer that resemble the tumor state, suggesting oncogenic memory and potential therapeutic targets.
bioRxiv · Jan 23, 2020 · PreprintCancer Biology