Author

D. C. Sevin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 1 Cell Biology· 1 Microbiology· 1 Physiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 3 Approach:statistical model· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:metabolomics· 2 Organism:mouse· 2 Assay:proteomics· 2

Frequent Co-Authors

D. Poeckel· 2 shared G. Bergamini· 2 shared J. Vappiani· 2 shared K. R. Patil· 2 shared A. Alladin· 1 shared A. Halavatyi· 1 shared A. J. Fisher· 1 shared A. Rutkowska· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersPhysiology

D. Poeckel

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Consistency across multi-omics layers in a drug-perturbed gut microbial community

S. Wuyts, R. Alves, M. Zimmermann-Kogadeeva, S. Nishijima, S. Blasche, M. Driessen, P. E. Geyer, R. Hercog, E. Kartal, L. Maier, J. B. Müller, S. Garcia Santamarina, T. S. B. Schmidt, D. C. Sevin, A. Telzerow, , P. Bork

The paper examines consistency and complementarity across five omics layers in a drug-perturbed gut microbial community, finding high agreement in species abundance and functional insights from different data types.

bioRxiv · Jan 3, 2023Microbiology

Oncogenic memory underlying minimal residual disease in breast cancer

K. R. Shechter, E. Kafkia, K. Zirngibl, S. Gawrzak, A. Alladin, D. Machado, C. Luechtenborg, D. C. Sevin, B. Bruegger, K. R. Patil, M. Jechlinger

This study identifies metabolic features of minimal residual disease (MRD) cells in breast cancer that resemble the tumor state, suggesting oncogenic memory and potential therapeutic targets.

bioRxiv · Jan 23, 2020 · PreprintCancer Biology

Multiomic and quantitative label-free microscopy-based analysis of ex vivo culture and TGFbeta1 stimulation of human precision-cut lung slices

M. M. Khan, D. Poeckel, A. Halavatyi, F. Stein, J. Vappiani, D. C. Sevin, C. Tischer, N. Zinn, J. D. Eley, N. S. Gudmann, T. Muley, H. Winter, A. J. Fisher, C. B. nanthakumar, G. Bergamini, R. Pepperkok

The paper uses multiomic and microscopy techniques to study fibrosis in human lung slices, showing increased collagen deposition with TGFbeta1 stimulation and a novel SHG-based method to quantify it.

bioRxiv · Dec 13, 2019Physiology

Proteome thermal stability reflects organ physiology and identifies drug-target engagement in vivo

J. Perrin, T. Werner, N. Kurzawa, D. D. Childs, M. Kalxdorf, A. Rutkowska, D. Poeckel, D. C. Sevin, E. Stonehouse, K. Strohmer, B. Heller, D. Thomson, J. Vappiani, J. Krause, H. C. Eberl, , G. Bergamini

This study introduces tissue-TPP and blood-CETSA to measure proteome thermal stability, revealing organ physiology and drug-target engagement in vivo.

bioRxiv · Dec 20, 2018 · PreprintCell Biology