Author

D. Machado

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Cancer Biology· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:metagenomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1

Frequent Co-Authors

K. R. Patil· 3 shared E. Kafkia· 2 shared Y. Kim· 2 shared A. Alladin· 1 shared A. Rivera-Colon· 1 shared A. Suh· 1 shared B. Bruegger· 1 shared B. Petersen· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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3 shared papersMicrobiology

K. R. Patil

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

The genomic basis of the plant island syndrome in Darwin's giant daisies

J. Cerca, B. Petersen, J. M. Lazaro Guevara, A. Rivera-Colon, S. Birkeland, J. Vizueta, S. Li, J. Loureiro, C. Kosawang, P. Jaramillo Diaz, G. Rivas-Torres, M. Fernandez-Mazuecos, P. Vargas, R. McCauley, G. Petersen, , M. D. Martin

This study characterizes the genomic basis of the plant island syndrome in Darwin's giant daisies by analyzing the genome of Scalesia atractyloides, identifying subgenomes, polyploidization events, and genes under selection.

bioRxiv · Jan 26, 2022Evolutionary Biology

Polarization of microbial communities between competitive and cooperative metabolism

D. Machado, O. M. Maistrenko, S. Andrejev, Y. Kim, P. Bork, K. R. Patil, K. R. Patil

The paper analyzes microbial community composition across habitats, revealing two distinct types characterized by competition or cooperation, and links cooperation to gut colonization by probiotics.

bioRxiv · Jan 28, 2020Microbiology

Oncogenic memory underlying minimal residual disease in breast cancer

K. R. Shechter, E. Kafkia, K. Zirngibl, S. Gawrzak, A. Alladin, D. Machado, C. Luechtenborg, D. C. Sevin, B. Bruegger, K. R. Patil, M. Jechlinger

This study identifies metabolic features of minimal residual disease (MRD) cells in breast cancer that resemble the tumor state, suggesting oncogenic memory and potential therapeutic targets.

bioRxiv · Jan 23, 2020 · PreprintCancer Biology

Emergence of stable coexistence in a complex microbial community through metabolic cooperation and spatio-temporal niche partitioning

S. Blasche, Y. Kim, R. Mars, E. Kafkia, M. Maansson, D. Machado, B. Teusink, J. Nielsen, V. Benes, R. Neves, U. Sauer, K. R. Patil

This study shows how kefir, a natural microbial community, achieves stable coexistence through spatio-temporal niche partitioning and metabolic cooperation during milk fermentation.

bioRxiv · Feb 22, 2019 · PreprintMicrobiology