K. R. Patil

Gut microbiome remains stable following COVID-19 vaccination in healthy and immuno-compromised individuals

This study shows that the gut microbiome remains stable after COVID-19 vaccination in both healthy and immuno-compromised individuals, with no significant changes in diversity, phylum, species, or functional capacity.

Emergence of community behaviors in the gut microbiota upon drug treatment

This study examines how drug treatment affects gut microbiota communities, finding that cross-protection is more common than cross-sensitization, and that metabolic processes contribute to these community behaviors.

Consistency across multi-omics layers in a drug-perturbed gut microbial community

The paper examines consistency and complementarity across five omics layers in a drug-perturbed gut microbial community, finding high agreement in species abundance and functional insights from different data types.

Fluctuating environment can negate cheater success due to speed-agility trade-off

The paper shows that fluctuating environments can suppress cheaters in microbial cooperation through a speed-agility trade-off, stabilizing cooperation in nutrient availability changes.

CRISPRi screens reveal genes modulating yeast growth in lignocellulose hydrolysate

The paper uses CRISPRi screens in yeast to identify genes affecting growth in lignocellulose hydrolysate, revealing known and new targets for improving industrial fermentation.

Polarization of microbial communities between competitive and cooperative metabolism

The paper analyzes microbial community composition across habitats, revealing two distinct types characterized by competition or cooperation, and links cooperation to gut colonization by probiotics.

Oncogenic memory underlying minimal residual disease in breast cancer

This study identifies metabolic features of minimal residual disease (MRD) cells in breast cancer that resemble the tumor state, suggesting oncogenic memory and potential therapeutic targets.

Dissecting the collateral damage of antibiotics on gut microbes

This study characterizes the antibiotic activity spectrum on gut bacteria, revealing species-specific effects and identifying antidotes to mitigate collateral damage.

Emergence of stable coexistence in a complex microbial community through metabolic cooperation and spatio-temporal niche partitioning

This study shows how kefir, a natural microbial community, achieves stable coexistence through spatio-temporal niche partitioning and metabolic cooperation during milk fermentation.