Dietary sulfur amino acid restriction improves glucose homeostasis through hepatic de novo serine synthesis
Andres F. Ortega, Cha Mee Vang, Ferrol I. Rome, Kaitlyn M. Andreoni, Aiden M. Phoebe, Alisa B. Nelson, Peter A. Crawford, James J. Galligan, Stanley Ching‐Cheng Huang, Curtis C. Hughey
This study shows that dietary sulfur amino acid restriction improves glucose homeostasis by enhancing hepatic de novo serine synthesis through PSAT1, but not lipid metabolism.
Molecular Metabolism · Feb 4, 2026Peer-reviewedPhysiology