PhysiologybioRxivPreprint
Sulfur amino acid restriction prevents S-adenosylmethionine-driven liver steatosis, hepatocellular carcinoma, and metabolic remodeling in high-fat-fed GNMT-null mice
Griffin S Hampton, Andres F. Ortega, Cha Mee Vang…·Curtis C. Hughey
This study shows that sulfur amino acid restriction prevents liver steatosis and hepatocellular carcinoma in GNMT-null mice fed a high-fat diet by reducing SAM levels and metabolic dysregulation.
DOI 10.64898/2026.07.17.738958