Curtis C. Hughey

This study shows that sulfur amino acid restriction prevents liver steatosis and hepatocellular carcinoma in GNMT-null mice fed a high-fat diet by reducing SAM levels and metabolic dysregulation.

This study shows that (R,S)-1,3-butanediol improves memory in female tauopathy mice on chow but not on high-fat diets or after long-term use, highlighting sex and diet-dependent cognitive benefits.

This study shows that dietary sulfur amino acid restriction improves glucose homeostasis by enhancing hepatic de novo serine synthesis through PSAT1, but not lipid metabolism.

This study shows that mitochondrial citrate metabolism and efflux regulate trophoblast differentiation through effects on histone acetylation and gene expression.