High-throughput High Content Quantification of HIV-1 Viral Infectious Output
Teresa LuPone, Alexis Brantly, Oluwatofunmi Oteju, Stephanie M. Matt, Kaitlyn Runner, Emily A. Nickoloff-Bybel, Michael R. Nonnemacher, Peter J. Gaskill
This paper introduces a high-content imaging assay to quantify HIV-1 infectivity using modified osteosarcoma cells, enabling rapid and consistent evaluation of viral replication dynamics.
bioRxiv · Jun 28, 2025 · PreprintMicrobiology