Temporal analysis suggests a reciprocal relationship between 3D chromatin structure and transcription
Kathleen S Metz Reed, Eric S. Davis, Marielle L. Bond, Alan Cabrera, Eliza Thulson, Ivana Yoseli Quiroga, Shannon Cassel, Kamisha T. Woolery, Isaac B. Hilton, Hyejung Won, Michael I. Love, Douglas H. Phanstiel
The paper analyzes temporal changes in chromatin structure and gene expression during macrophage activation, finding a reciprocal relationship between loops and transcription.
Cell Reports · Nov 1, 2022Peer-reviewedGenomics