Kathleen S Metz Reed

The paper identifies DNA replication machinery components as critical for TAD boundary re-establishment during DNA replication.

The paper profiles genome organization changes during breast cancer progression using Micro-C mapping and links these changes to gene expression and enhancer activity.

The paper develops an AMC model to link multiway enhancer-promoter contacts and enhancer activity to gene overexpression in prostate and breast cancer.

The paper investigates the relationship between TAD boundaries and gene activity using single-cell imaging, finding they are largely uncoupled.

This study shows that acute RUNX1 loss reprograms enhancer activity, leading to epithelial destabilization and cancer hallmark activation in human mammary epithelial cells.

The paper analyzes temporal changes in chromatin structure and gene expression during macrophage activation, finding a reciprocal relationship between loops and transcription.

The paper assesses the transcriptional response of in vitro innate immune cell models to synthetic amyloid beta and finds no robust response, but identifies LPS and INFγ as better activators of microglia-like cells.

This study examines the transcriptional response of human chondrocytes to fibronectin fragments, finding similarities to osteoarthritis gene expression patterns.

Coral provides an interactive web tool for visualizing human kinome data with customizable features and high-resolution outputs.