A single cluster of RNA Polymerase II molecules is stably associated with active genes
Apratim Mukherjee, Manya Kapoor, Kareena Shankta, Samantha Fallacaro, Raymond D. Carter, Gabriela Hayward-Lara, Puttachai Ratchasanmuang, Yara I. Haloush, Mustafa Mir
The paper investigates RNAPII clustering during ZGA in Drosophila embryos, showing clusters are stably associated with active genes and reflect transcriptional activity, not phase separation.
Nature Communications · Mar 20, 2026Peer-reviewedBiophysics