Author

Manya Kapoor

Children's Hospital of PhiladelphiaORCID 0000-0002-0352-5131Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:cell signaling & trafficking· 2 Organism:Drosophila· 2 Assay:imaging· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Approach:experimental assay· 1

Frequent Co-Authors

Mustafa MiriD· 3 shared Apratim MukherjeeiD· 2 shared Samantha FallacaroiD· 2 shared Gabriela Hayward-LaraiD· 1 shared Hernán G. GarcíaiD· 1 shared Kareena Shankta· 1 shared Lillian EncarnationiD· 1 shared Meghan A. TurneriD· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersBiophysics

Mustafa MirORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Enhancer binding kinetics explain transcription factor hub formation

Samantha Fallacaro, Manya Kapoor, Lillian Encarnation, Apratim Mukherjee, Meghan A. Turner, Hernán G. García, Mustafa Mir

The paper uses live-imaging and computational modeling to show that Dorsal hub formation in Drosophila embryos depends on TF-DNA binding kinetics, not enhancer sequence or higher-order regulatory structures.

Science Advances · Oct 9, 2026Peer-reviewedBiophysics

Molecular diffusion and binding kinetics are sufficient to explain condensate-like nuclear clustering

Manya Kapoor, Mustafa Mir

The paper develops a computational model to show that molecular diffusion and binding kinetics can explain nuclear protein clustering without requiring phase separation or protein-protein interactions.

bioRxiv · Jun 6, 2026 · PreprintBiophysics

A single cluster of RNA Polymerase II molecules is stably associated with active genes

Apratim Mukherjee, Manya Kapoor, Kareena Shankta, Samantha Fallacaro, Raymond D. Carter, Gabriela Hayward-Lara, Puttachai Ratchasanmuang, Yara I. Haloush, Mustafa Mir

The paper investigates RNAPII clustering during ZGA in Drosophila embryos, showing clusters are stably associated with active genes and reflect transcriptional activity, not phase separation.

Nature Communications · Mar 20, 2026Peer-reviewedBiophysics