Developmental BiologyJCI InsightPeer-reviewed
S1PR1 regulates the quiescence of lymphatic vessels by inhibiting laminar shear stress-dependent VEGF-C signaling
Xin Geng, Keisuke Yanagida, Racheal Grace Akwii…·R. Sathish Srinivasan
This study identifies S1PR1 as a regulator of lymphatic vessel quiescence by inhibiting LSS-dependent VEGF-C signaling in lymphatic endothelial cells.
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