Author

Kari M. Brown

Cincinnati Children's Hospital Medical Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 2

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:Hi-C· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Samantha A. BrugmanniD· 2 shared Andrea Scarpa WildermaniD· 1 shared Ching‐Fang ChangiD· 1 shared Daniel T. Rasicci· 1 shared Danny E. MilleriD· 1 shared Ellen RoetsiD· 1 shared Emma Wentworth WinchesteriD· 1 shared Eva D’haeneiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersDevelopmental Biology

Samantha A. BrugmannORCID

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2 papers

Recent·Most cited

Targeting SUFU-mediated GLI activity alleviates ciliopathic phenotypes

Ching‐Fang Chang, Yanfen Yang, Kari M. Brown, Daniel T. Rasicci, Timothy Nguyen, Kevin A. Peterson, Samantha A. Brugmann

This study shows that modulating SUFU-GLI interactions rescues ciliopathic phenotypes in mice by restoring GLI transcriptional activity without requiring ciliary processing.

bioRxiv · Oct 26, 2026 · PreprintDevelopmental Biology

A distant global control region is essential for normal expression of anterior HOXA genes during mouse and human craniofacial development.

Andrea Scarpa Wilderman, Eva D’haene, Machteld Baetens, Tara N. Yankee, Emma Wentworth Winchester, Nicole C. Glidden, Ellen Roets, Jo Van Dorpe, Sandra Janssens, Danny E. Miller, Miranda Galey, Kari M. Brown, Rolf W. Stottmann, Sarah Vergult, K. Nicole Weaver, , Justin L. Cotney

The paper identifies a critical noncoding superenhancer region essential for regulating anterior HOXA genes in craniofacial development, showing its deletion causes severe developmental defects in mice and a human patient.

Nature Communications · Jan 2, 2024Peer-reviewedDevelopmental Biology