Author

Nicole C. Glidden

UConn Health

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Developmental Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 2 Organism:human· 2 Organism:mouse· 2 Approach:statistical model· 2 Assay:DNA methylation· 1 Approach:experimental assay· 1 Assay:Hi-C· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Aaron ShulkiniD· 1 shared Abigail Sondrini· 1 shared Alberto BosqueiD· 1 shared Alicja K. TrochaiD· 1 shared Alper KüçükuraliD· 1 shared Amanda Modica· 1 shared Andrea Scarpa WildermaniD· 1 shared Carol J. BultiD· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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1 shared paperImmunology

Aaron ShulkinORCID

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Author profile →

3 papers

Recent·Most cited

Loss of Vpr-driven TRAIL-R2 expression protects HIV-infected cells from non-canonical NK cell TRAIL attack

Paula E. Grasberger, Abigail Sondrini, Nicole C. Glidden, Amanda Modica, Natalie Pushlar, Seden Bedir, Tara Bromfield, Sheldon Gentling, Komal Cheema, Alper Küçükural, Milena Ozdemir, Maria L. Zapp, Alberto Bosque, Louise Leyre, Aaron Shulkin, , Kiera Clayton

The paper shows HIV uses Vpr to increase TRAIL-R2 expression in CD4+ T cells, which enhances NK cell killing through non-canonical TRAIL signaling.

bioRxiv · Apr 19, 2026 · PreprintImmunology

A distant global control region is essential for normal expression of anterior HOXA genes during mouse and human craniofacial development.

Andrea Scarpa Wilderman, Eva D’haene, Machteld Baetens, Tara N. Yankee, Emma Wentworth Winchester, Nicole C. Glidden, Ellen Roets, Jo Van Dorpe, Sandra Janssens, Danny E. Miller, Miranda Galey, Kari M. Brown, Rolf W. Stottmann, Sarah Vergult, K. Nicole Weaver, , Justin L. Cotney

The paper identifies a critical noncoding superenhancer region essential for regulating anterior HOXA genes in craniofacial development, showing its deletion causes severe developmental defects in mice and a human patient.

Nature Communications · Jan 2, 2024Peer-reviewedDevelopmental Biology

Genetic mapping in Diversity Outbred mice identifies a Trpa1 variant influencing late phase formalin response

Jill M. Recla, Jason A. Bubier, Daniel M. Gatti, Jennifer L. Ryan, Katie H. Long, Raymond F. Robledo, Nicole C. Glidden, Guoqiang Hou, Gary A. Churchill, Richard S. Maser, Zhongwei Zhang, Erin E. Young, Elissa J. Chesler, Carol J. Bult

This study identifies a Trpa1 splice junction variant in Diversity Outbred mice that influences late phase formalin response, linking it to pain sensitivity mechanisms.

Pain · Mar 27, 2019Peer-reviewedBioinformatics