Author

Karla Soriano

Northwestern University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Neuroscience· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Organism:human· 2 Research Focus:drug response / drug discovery· 1 Assay:electronic health records· 1

Frequent Co-Authors

Richard S. SmithiD· 2 shared Sean R Golinski· 2 shared Alex C. BriegeliD· 1 shared Anusha Doddi· 1 shared Christie N CambridgeiD· 1 shared Christopher A. WalshiD· 1 shared Chunhui CaiiD· 1 shared David Exposito-AlonsoiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersNeuroscience

Richard S. SmithORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Pannexin-1 regulates cellular identity and excitability in the developing cortex

Norma K. Hylton, David J Kang, Steven C. Decker, David Exposito-Alonso, Christie N Cambridge, Sean R Golinski, Karla Soriano, Madeline C. Burke, Ximena Gómez-Maqueo, Qiurui Chen, Ruilong Hu, Jennifer N. Partlow, Maya Talukdar, Rebecca Andersen, Trenton M Buckner, , Richard S. Smith

This study identifies de novo PANX1 mutations in individuals with PMG and microcephaly, showing they disrupt glycosylation, increase ATP release, and alter cortical development through ion conductance and cell fate regulation.

bioRxiv · Aug 26, 2026 · PreprintNeuroscience

Gene therapy for targeting a prenatally enriched potassium channel associated with severe childhood epilepsy and premature death

Sean R Golinski, Karla Soriano, Alex C. Briegel, Madeline Burke, Timothy W. Yu, Tojo Nakayama, Ruing Hu, Richard S. Smith

The paper demonstrates that ASO therapy targeting KCNT1 reduces seizures in a severe childhood epilepsy condition by normalizing neuronal function in prenatally enriched neurons.

bioRxiv · Oct 24, 2024 · PreprintNeuroscience