Genome-scale label-free imaging reveals cellular physiology encoded in bacterial collective architecture
Seh Na Mellick, Jesse J. Derringer, Darin Boyes, Gillian Croteau, Madeline Burke, Steven Gifford, Drew C. Stark, Laura A. Mike, Sophia Turecki, Oana Carja, Irina V. Mikheyeva, Andrew A. Bridges
The paper introduces PULLI, a computer vision platform that extracts phenotypes from bacterial growth timelapses, revealing genotype-phenotype relationships in Vibrio cholerae mutants.
bioRxiv · Aug 31, 2026 · PreprintMicrobiology