TRAIL-induced cytokine production via NFKB2 pathway promotes neutrophil chemotaxis and immune suppression in triple negative breast cancers
Manjari Kundu, Yoshimi Endo Greer, Alexei V. Lobanov, Lisa A. Ridnour, Renee Nicole Donahue, Yeap Ng, Shashi Ratnayake, Karley White, Donna M. Voeller, Sarah Weltz, Qingrong Chen, Stephen Lockett, Maggie Cam, Daoud M. Meerzaman, David A. Wink, , Stanley Lipkowitz
This study shows TRAIL treatment of TNBC cells activates the NFKB2 pathway, leading to cytokine production that enhances neutrophil chemotaxis and immune suppression.
Cancer Letters · Apr 6, 2025Peer-reviewedCancer Biology