Author

Yeap Ng

National Institutes of HealthORCID 0000-0002-5702-8296Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Organism:human· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Roberto WeigertiD· 3 shared Alexei V. LobanoviD· 1 shared Bhagawat C. SubramanianiD· 1 shared Brad BelliD· 1 shared Brad St. CroixiD· 1 shared Carole A. ParentiD· 1 shared Daoud M. MeerzamaniD· 1 shared David A. WinkiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersCancer Biology

Roberto WeigertORCID

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3 papers

Recent·Most cited

Spatially Distinct Myosin II Architectures Regulate Protrusion Dynamics and Directional Persistence during Immune Cell Migration

Nicolas Mélis, Desu Chen, Emily Chen, Thomas Daugbjerg Madsen, Yeap Ng, Bhagawat C. Subramanian, Weiye Wang, Carole A. Parent, Wolfgang Losert, Roberto Weigert

This study identifies two spatially distinct myosin II architectures in neutrophils that coordinate protrusion dynamics and directional persistence during migration.

bioRxiv · Mar 16, 2026 · PreprintCell Biology

Dissection of Gαs and Hedgehog signaling crosstalk reveals therapeutic opportunities to target adenosine receptor 2b in Hedgehog-dependent tumors

Sarah Krantz, Brad Bell, Katherine Lund, Natalia Salinas Parra, Yeap Ng, Natalia De Oliveira Rosa, Saikat Mukhopadhyay, Brad St. Croix, Kavita Yang Sarin, Roberto Weigert, Francesco Raimondi, Ramiro Iglesias‐Bartolomé

The paper identifies Gs pathway inactivation as an SMO-independent Hedgehog signaling driver in BCC and shows adenosine 2B receptor activation can counteract SMO-driven oncogenesis.

Cancer Research · Dec 29, 2025Peer-reviewedCancer Biology

TRAIL-induced cytokine production via NFKB2 pathway promotes neutrophil chemotaxis and immune suppression in triple negative breast cancers

Manjari Kundu, Yoshimi Endo Greer, Alexei V. Lobanov, Lisa A. Ridnour, Renee Nicole Donahue, Yeap Ng, Shashi Ratnayake, Karley White, Donna M. Voeller, Sarah Weltz, Qingrong Chen, Stephen Lockett, Maggie Cam, Daoud M. Meerzaman, David A. Wink, , Stanley Lipkowitz

This study shows TRAIL treatment of TNBC cells activates the NFKB2 pathway, leading to cytokine production that enhances neutrophil chemotaxis and immune suppression.

Cancer Letters · Apr 6, 2025Peer-reviewedCancer Biology