NeurosciencebioRxivPreprint
Piccolo Regulates Secretion of the Extracellular Matrix Components Brevican and Tenascin R from Astrocytes to Drive Synapse Formation: Implications for Pontocerebellar Hypoplasia Type 3 (PCH3)
Maryam Mohamaddokht, Joanne E. Falck, Sanra Kumsal Öktem…·Frauke Ackermann
This study identifies Piccolo's role in astrocytic ECM secretion, showing its impact on synapse formation and neuronal network activity in PCH3.
DOI 10.1101/2025.07.03.662734