Author
University Hospital Carl Gustav Carus
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
4 papers
Recent·Most cited
Oleksandra Topcheva, Andreas S. Mueller, Marcelo Zoccoler…·Michele Solimena
This study shows that cationic amphiphilic drugs (CADs) accumulate in insulin secretory granules via pH-dependent trapping, affecting monoamine storage and pH regulation.
Hassan Mziaut, Preethi Kesavan, Chunguang Chen…·Michele Solimena
This study shows that the Villin-SNAP25 interaction regulates insulin secretion by controlling secretory granule docking sites in response to glucose levels.
Klaus-Peter Knoch, Antonia Kosok, Zuzana Mariničová…·Michele Solimena
This study shows that EVs deplete GGA2 in beta cells, causing Golgi acidification and altering the MHC class I immunopeptidome through premature cathepsin activation.
Esteban Quezada, Jovana Vasiljević, Akshaye Pal…·Michele Solimena
The paper shows that G3BP1/2 form condensates with insulin mRNA in beta cells, which dissolve upon glucose stimulation, regulating insulin mRNA storage and translation.