Author

Oleksandra Topcheva

Paul Langerhans Institute DresdenORCID 0000-0003-2010-2410Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Andreas S. Mueller· 1 shared Anke Sönmez· 1 shared Carla Münster· 1 shared Carolin Wegbrod· 1 shared Juha M. Torkko· 1 shared Katharina Ganß· 1 shared Klaus-Peter KnochiD· 1 shared Marcelo ZoccoleriD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

Andreas S. Mueller

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1 paper

Recent·Most cited

Cell BiologybioRxivPreprintFeb 20, 2026

pH-dependent trapping of cationic amphiphilic drugs perturbs insulin granule homeostasis

Oleksandra Topcheva, Andreas S. Mueller, Marcelo Zoccoler…·Michele Solimena

This study shows that cationic amphiphilic drugs (CADs) accumulate in insulin secretory granules via pH-dependent trapping, affecting monoamine storage and pH regulation.

DOI 10.64898/2026.02.19.706757

mouseproteomics

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