mTORC1 signaling is not essential for the maintenance of muscle mass and function in adult sedentary mice
Alexander S. Ham, Kathrin Chojnowska, Lionel A. J. Tintignac, Shuo Lin, Alexander Schmidt, Daniel J. Ham, Michael Sinnreich, Markus A. Rüegg
This study shows that mTORC1 inhibition in adult mice does not cause muscle atrophy or functional decline, despite metabolic and morphological changes.
bioRxiv · Aug 19, 2019 · PreprintMolecular Biology