Septin7 is essential in early hematopoiesis, but redundant at later stages
Natalia Ronkina, Nikita A. Verheyden, Prerna Gambhir, Kathrin Laaß, Tatiana Yakovleva, Anneke Doerrie, Megha Abbey, M. Menon, Anton Selich, Melanie Galla, Michael Rothe, Axel Schambach, Stephanie Buchheister, Andreas Krueger, Alexey Kotlyarov, Matthias Gaestel
This study shows Septin7 is essential for early hematopoiesis but dispensable at later stages, as its deletion in hematopoietic cells leads to engraftment failure but not steady-state blood lineage defects.
Life Science Alliance · Jul 13, 2026Peer-reviewedBiochemistry