M. Menon

This study shows that 5-Iodotubercidin inhibits EMT by suppressing NFκB-dependent gene expression, and identifies a gene signature predictive of survival in lung and pancreatic cancer.

The paper identifies over 4000 bifunctional genes in the human genome, which produce both coding and non-coding transcripts, and presents a database of their potential functions.

This study shows Septin7 is essential for early hematopoiesis but dispensable at later stages, as its deletion in hematopoietic cells leads to engraftment failure but not steady-state blood lineage defects.

This study identifies a Cdc42-Borg4-Sep7 axis that regulates HSC polarity and function by controlling the polar distribution of these proteins and affecting engraftment potential and LMPP frequency.

The paper analyzes SARS-CoV-2 mutations across 1448 genomes, identifying five mutually exclusive clusters and lineage-defining mutations with geographic distribution patterns.

The paper identifies an alternative translation initiation site in MK2 mRNA that generates a long isoform with distinct functional properties compared to the short isoform.