YTHDF1 mediates translational control by m6A mRNA methylation in adaptation to environmental challenges
Zhuoyue Shi, Kailong Wen, Wenqin Fu, Zhongyu Zou, Kathryn Guo, Nabilah H. Sammudin, Meera J. Patel, Xiangbin Ruan, Shivang Sullere, Shuai Wang, Xiaochang Zhang, Gopal Thinakaran, Chuan He, Xiaoxi Zhuang
This study shows that YTHDF1 mediates m6A mRNA methylation in neuronal adaptation to environmental challenges, with distinct roles in D1 and D2 neurons.
Proceedings of the National Academy of Sciences · Apr 13, 2026Peer-reviewedNeuroscience