Zhongyu Zou

This paper shows that 5-azaC induces leukemia cell death by depleting m5C in chromatin-associated RNA, leading to transcriptional repression and disrupting key regulatory pathways.

This study shows that YTHDF1 mediates m6A mRNA methylation in neuronal adaptation to environmental challenges, with distinct roles in D1 and D2 neurons.

This study identifies FUBP1 as an Nm-binding protein and shows it regulates splicing by binding to Nm-modified intronic regions.

This study shows that FMRP phosphorylation regulates neuronal translation via YTHDF1, revealing a mechanism for FXS pathology and suggesting YTHDF1 as a therapeutic target.

This study investigates the role of m6A methylation in early pancreatic β-cell differentiation in humans and mice, showing METTL14's essential role in this process.