Functional screen for mediators of onco-mRNA translation specificity
Joanna R. Kovalski, Goksu Sarioglu, Vishvak Subramanyam, Grace A. Hernandez, Gilles Rademaker, Juan A. Osés-Prieto, Macey J. Slota, Nimmy Mohan, Kaylee Yiakis, Isabelle Liu, Kwun Wah Wen, Grace Kim, Sohit Miglani, Alma L. Burlingame, Hani Goodarzi, , Davide Ruggero
The paper identifies RBM42 as a key regulator of MYC translation in PDAC, showing its role in oncogenic transcript regulation and tumor growth.
Nature Cell Biology · Feb 4, 2025Peer-reviewedCancer Biology