Author

Sohit Miglani

University of California, San FranciscoORCID 0000-0002-8075-320XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2 Systems Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Hani GoodarziiD· 3 shared Johnny X. YuiD· 2 shared Vishvak SubramanyamiD· 2 shared Albertas NavickasiD· 1 shared Alma L. BurlingameiD· 1 shared Andrey BuyaniD· 1 shared Anthony Doty· 1 shared Beatrice GiniiD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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3 shared papersCancer Biology

Hani GoodarziORCID

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3 papers

Recent·Most cited

Actionable biological programs to enhance EGFR-targeted therapy response unveiled by single-cell lineage tracing in clinically relevant lung cancer models

Beatrice Gini, Whitney Tamaki, Johnny X. Yu, Dora Barbosa, Wei Wu, Yashar Pourmoghadam, Paul Allegakoen, Donghwa Kim, Sohit Miglani, Sarah Elmes, Victor R. Olivas, Hani Goodarzi, Trever Grant Bivona

This study uses single-cell lineage tracing and RNAseq to identify pre-existing resistant tumor subclones in lung cancer models and their transcriptional programs, revealing mechanisms of therapy resistance.

bioRxiv · May 19, 2025 · PreprintCancer Biology

Functional screen for mediators of onco-mRNA translation specificity

Joanna R. Kovalski, Goksu Sarioglu, Vishvak Subramanyam, Grace A. Hernandez, Gilles Rademaker, Juan A. Osés-Prieto, Macey J. Slota, Nimmy Mohan, Kaylee Yiakis, Isabelle Liu, Kwun Wah Wen, Grace Kim, Sohit Miglani, Alma L. Burlingame, Hani Goodarzi, , Davide Ruggero

The paper identifies RBM42 as a key regulator of MYC translation in PDAC, showing its role in oncogenic transcript regulation and tumor growth.

Nature Cell Biology · Feb 4, 2025Peer-reviewedCancer Biology

Systematic Identification of Post-Transcriptional Regulatory Modules

Matvei Khoroshkin, Andrey Buyan, Martin Dodel, Albertas Navickas, Johnny X. Yu, Fathima Trejo, Anthony Doty, Rithvik Baratam, Shaopu Zhou, Sean Bong Lee, Tanvi V. Joshi, Kristle Garcia, Man Hung Choi, Sohit Miglani, Vishvak Subramanyam, , Hani Goodarzi

The paper systematically identifies post-transcriptional regulatory modules by integrating multimodal data on RBP interactions and functions.

Nature Communications · Sep 9, 2024Peer-reviewedSystems Biology