Author
University of California, San FranciscoORCID 0000-0001-6494-6194Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Paige V. Halas, Hannah Savage, Stephanie J. Hachey…·Devon A. Lawson
This study identifies PHLDA2 as a driver of breast cancer metastasis by reactivating a placental vascular remodeling program through hypomethylation and SPARC-mediated effects.
Gilles Rademaker, Grace A. Hernandez, Sumena Dahal…·Rushika M. Perera
This study identifies PCSK9 as a key determinant of metastatic organ preference in pancreatic cancer by regulating cholesterol acquisition and utilization in liver versus lung environments.
Aakriti Jain, Isaac P. Heremans, Gilles Rademaker…·Roberto Zoncu
The paper identifies LyLAP as a key enzyme for lysosomal degradation of transmembrane proteins, showing its role in maintaining endocytic activity and lysosomal stability in pancreatic cancer.
Joanna R. Kovalski, Goksu Sarioglu, Vishvak Subramanyam…·Davide Ruggero
The paper identifies RBM42 as a key regulator of MYC translation in PDAC, showing its role in oncogenic transcript regulation and tumor growth.