Sialic Acid Identity Modulates Host Tropism of Sialoglycan-binding Viridans Group Streptococci
KeAndreya M. Morrison, Rupesh Agarwal, Haley Stubbs, Hai Yu, Stefan Rühl, Xi Chen, Paul M. Sullam, Barbara A. Bensing, Jeremy C. Smith, T.M. Iverson
This study shows that sialic acid identity influences, but does not solely determine, host tropism of sialoglycan-binding streptococci by testing binding preferences of SLBRs to Neu5Ac and Neu5Gc.
Journal of Biological Chemistry · Jul 30, 2025Peer-reviewedPathology