Rupesh Agarwal

This study shows that sialic acid identity influences, but does not solely determine, host tropism of sialoglycan-binding streptococci by testing binding preferences of SLBRs to Neu5Ac and Neu5Gc.

The paper designs small-molecule inhibitors of hIL-6 using computational screening and validates one compound's inhibitory effect on IL6-induced STAT3 activity.

This study identifies GPRC6A as a potential target for metformin's glucose-lowering effects, showing metformin activates GPRC6A in vitro and in vivo.

This study shows that osteocalcin binds to a distinct allosteric site in GPRC6A's VFT domain, acting as a positive modulator and enhancing its signaling.