fmo-4 promotes longevity and stress resistance via ER to mitochondria calcium regulation in C. elegans
Angela M. Tuckowski, Safa Beydoun, Elizabeth S. Kitto, Ajay Bhat, Marshall B. Howington, Aditya Sridhar, Mira Bhandari, Kelly Chambers, Scott F. Leiser
This study shows that fmo-4 in C. elegans extends lifespan and stress resistance by regulating calcium homeostasis through interactions with known longevity pathways.
eLife · Feb 14, 2025Peer-reviewedGenetics