Complementary vertebrate Wac models exhibit phenotypes relevant to DeSanto-Shinawi Syndrome
Kang‐Han Lee, April M Stafford, Maria Pacheco-Vergara, Karol Cichewicz, César P. Canales, Nicolas Seban, Melissa Corea, Darlene Rahbarian, Kelly E. Bonekamp, Grant R. Gillie, Dariangelly Pacheco-Cruz, Alyssa M Gill, Hye-Eun Hwang, Yeong-Eun Kim, Katie L Uhl, , Daniel L. Vogt
The paper develops murine and zebrafish Wac deletion models to study DeSanto-Shinawi Syndrome, finding craniofacial, behavioral, and neurodevelopmental phenotypes similar to the human condition.
eLife · Sep 3, 2026Peer-reviewedNeuroscience