Author
Nicolas Seban
University of California, DavisORCID 0000-0002-6737-6681Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2024-2026 · peak 4/yrCo-Author Collaboration Network
10 top collaborators · 45 mutual co-author links7 papers
Recent·Most cited
- PhysiologyeLifePeer-reviewedDOI 10.7554/elife.109237.3
- NeurosciencebioRxivPreprint
Precocious maturation and Purkinje cell dysfunction in the mouse Chd8 haploinsufficient cerebellum
Nicolas Seban, Esteban Merino, Alexa F. D’Ambra…·Alex S. Nord
This study examines the effects of Chd8 haploinsufficiency on cerebellar development and function in mice, revealing cell-type-specific transcriptomic and physiological changes.
- NeuroscienceeLifePeer-reviewed
Complementary vertebrate Wac models exhibit phenotypes relevant to DeSanto-Shinawi Syndrome
Kang‐Han Lee, April M Stafford, Maria Pacheco-Vergara…·Daniel L. Vogt
The paper develops murine and zebrafish Wac deletion models to study DeSanto-Shinawi Syndrome, finding craniofacial, behavioral, and neurodevelopmental phenotypes similar to the human condition.
- NeurosciencebioRxivPreprint
Chd8 haploinsufficiency leads to molecular layer heterotopias and age-dependent cortical expansion
Felix A. Kyere, Ian Curtin, Ziquan Wei…·Jason L. Stein
This study identifies molecular layer heterotopias and age-dependent cortical expansion in Chd8 haploinsufficient mice, linking them to neuronal migration defects and autism-related brain overgrowth.
- Molecular BiologybioRxivPreprint
Molecular interactions of Chd8 in mouse brain highlights a role in chromatin-associated RNA processing
Emily Smith, César P. Canales, Mathew W. Kenaston…·Alex S. Nord
The paper identifies CHD8 interactions in mouse brain, revealing a role in chromatin-associated RNA processing and highlighting dosage sensitivity in neurodevelopmental disorders.
DOI 10.64898/2025.12.11.693549 - GenomicsbioRxivPreprint
Persistent cortical excitatory neuron dysregulation in adult Chd8 haploinsufficient mice.
César P. Canales, Stephanie A. Lozano, Nicholas Alonzo Frost…·Alex S. Nord
This study identifies persistent excitatory neuron dysfunction in Chd8 haploinsufficient mice through single nucleus transcriptomics and behavioral analysis.
- Developmental BiologyDevelopmental CellPeer-reviewed
Combinatorial transcription factor binding encodes cis-regulatory wiring of forebrain GABAergic neurogenesis
Rinaldo Catta-Preta, Susan Lindtner, Athéna Rebecca Ypsilanti…·Alex S. Nord
The paper identifies combinatorial TF-cRE interactions in mouse basal ganglia development, revealing modules that drive GABAergic neurogenesis and suppress other fates.