Author

Kenneth A. Longo

Proteostasis Therapeutics (United States)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Arun ThiruvalluvaniD· 1 shared Brad J. Geddes· 1 shared Carlos SpichigeriD· 1 shared Christian Enrique González-BillaultiD· 1 shared Claudio A. HetziD· 1 shared Cristian SaqueliD· 1 shared Daniel R. Henríquez· 1 shared Di WuiD· 1 shared

Activity by Year

2020-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Arun ThiruvalluvanORCID

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1 paper

Recent·Most cited

Insulin-like growth factor 2 (IGF2) protects against Huntington's disease through the extracellular disposal of protein aggregates

Paula García-Huerta, Paulina Troncoso-Escudero, Di Wu, Arun Thiruvalluvan, Marisol Cisternas-Olmedo, Daniel R. Henríquez, Lars Plate, Pedro Chaná‐Cuevas, Cristian Saquel, Peter Thielen, Kenneth A. Longo, Brad J. Geddes, Gerardo Zelmar Lederkremer, Neeraj Sharma, Marina Shenkman, , Claudio A. Hetz

This study identifies IGF2 as a disease modifier that reduces intracellular protein aggregates by promoting their extracellular disposal in Huntington's disease models.

Acta Neuropathologica · Jul 8, 2020Peer-reviewedNeuroscience