Christian Enrique González-Billault

This study links the neuroactive potential of the elderly gut microbiome to mental health and cognition in older adults with cognitive complaints.

This study shows that inhibiting ER-mitochondria Ca2+ flux is a new target for senolysis in therapy-induced senescence.

This study identifies Reticulon-1C as a locally synthesized axonal protein that modulates microtubule dynamics and axon outgrowth by regulating Spastin activity.

The paper examines the relationship between cardiometabolic factors, blood beta-amyloid, and white matter hyperintensities in dementia-free individuals with cognitive complaints, finding stronger associations with cardiometabolic markers.

This study shows that a short-term cyclic ketogenic diet improves memory and synaptic plasticity in aged mice by modulating the cAMP/PKA signaling pathway and cytoskeleton dynamics.

The paper identifies a metabolic switch in aging astrocytes through integrative network and transcriptome analysis, revealing changes in energy metabolism and potential targets for cognitive decline prevention.

This study conducts the first GWAS on Alzheimer's disease in South American populations, identifying shared genetic risk factors with European populations.

This study identifies IGF2 as a disease modifier that reduces intracellular protein aggregates by promoting their extracellular disposal in Huntington's disease models.