Author

Kenneth Arestang

Addenbrooke's Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetic & Genomic Medicine· 2 Genetics· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Assay:scRNA-seq· 2 Research Focus:cell type annotation· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Carl A. AndersoniD· 3 shared Miles ParkesiD· 3 shared Rebecca E. McIntyreiD· 3 shared Tim RaineiD· 3 shared Biljana BrezinaiD· 2 shared Bradley T. HarrisiD· 2 shared Charry Queen Caballes· 2 shared Claire Dawson· 2 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersGenetic & Genomic Medicine

Carl A. AndersonORCID

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Author profile →

3 papers

Recent·Most cited

Single-Cell RNA Sequencing of Terminal Ileal Biopsies Identifies Signatures of Crohn's Disease Pathogenesis.

Monika Krzak, Tobi Alegbe, D. Leland Taylor, Gareth‐Rhys Jones, Mennatallah Ghouraba, Michelle Strickland, Bradley T. Harris, Reem Satti, Kenneth Arestang, Lucia Ramirez-Navarro, Nilanga Nishad, Kimberly Ai Xian Cheam, Marcus Tutert, Matiss Ozols, Guillaume G. Noell, , Carl A. Anderson

The paper identifies molecular signatures of Crohn's disease using scRNA-seq data from terminal ileal biopsies, highlighting key cell types and pathways involved in disease pathogenesis.

Nature Genetics · Jun 15, 2026Peer-reviewedGenetic & Genomic Medicine

Cell-type-resolved genetic regulatory variation shapes inflammatory bowel disease risk

Tobi Alegbe, Bradley T. Harris, Laura Fachal, Lucia Ramirez-Navarro, Marcus Tutert, Monika Krzak, Mennatallah Ghouraba, Michelle Strickland, Matiss Ozols, Celeste E Cohen, Saniya Khullar, Eleonora Khabirova, Nikolaos I. Panousis, David Ochoa, Noor Wana, , Carl A. Anderson

The paper maps cell-type-specific eQTLs in IBD patients to identify effector genes and mechanisms linking genetic risk to disease.

medRxiv · Jun 24, 2025 · PreprintGenetic & Genomic Medicine

Somatic evolution in non-neoplastic IBD-affected colon

Sigurgeir Ólafsson, Rebecca E. McIntyre, Tim H. H. Coorens, Timothy M. Butler, Hyunchul Jung, Philip S. Robinson, Henry Lee-Six, Mathijs Arnoud Sanders, Kenneth Arestang, Claire Dawson, Monika Tripathi, Konstantina Strongili, Yvette E. Hooks, Michael R. Stratton, Miles Parkes, , Carl A. Anderson

The paper analyzes somatic mutations in colonic crypts of IBD patients and controls, finding higher mutation rates and clonal expansions in IBD-affected tissue.

Cell · Jul 21, 2020Peer-reviewedGenetics