Author

Charry Queen Caballes

Addenbrooke's Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetic & Genomic Medicine· 3

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Research Focus:gene regulatory network inference· 3 Organism:human· 3 Assay:scRNA-seq· 3 Approach:statistical model· 3 Research Focus:cell type annotation· 2 Research Focus:clustering· 1

Frequent Co-Authors

Biljana BrezinaiD· 3 shared Bradley T. HarrisiD· 3 shared Carl A. AndersoniD· 3 shared Cristina CotobaliD· 3 shared Gareth‐Rhys JonesiD· 3 shared Jasmin OstermayeriD· 3 shared Jason Skelton· 3 shared Lucia Ramirez-NavarroiD· 3 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersGenetic & Genomic Medicine

Biljana BrezinaORCID

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Author profile →

3 papers

Recent·Most cited

Single-Cell RNA Sequencing of Terminal Ileal Biopsies Identifies Signatures of Crohn's Disease Pathogenesis.

Monika Krzak, Tobi Alegbe, D. Leland Taylor, Gareth‐Rhys Jones, Mennatallah Ghouraba, Michelle Strickland, Bradley T. Harris, Reem Satti, Kenneth Arestang, Lucia Ramirez-Navarro, Nilanga Nishad, Kimberly Ai Xian Cheam, Marcus Tutert, Matiss Ozols, Guillaume G. Noell, , Carl A. Anderson

The paper identifies molecular signatures of Crohn's disease using scRNA-seq data from terminal ileal biopsies, highlighting key cell types and pathways involved in disease pathogenesis.

Nature Genetics · Jun 15, 2026Peer-reviewedGenetic & Genomic Medicine

Cell-type-resolved genetic regulatory variation shapes inflammatory bowel disease risk

Tobi Alegbe, Bradley T. Harris, Laura Fachal, Lucia Ramirez-Navarro, Marcus Tutert, Monika Krzak, Mennatallah Ghouraba, Michelle Strickland, Matiss Ozols, Celeste E Cohen, Saniya Khullar, Eleonora Khabirova, Nikolaos I. Panousis, David Ochoa, Noor Wana, , Carl A. Anderson

The paper maps cell-type-specific eQTLs in IBD patients to identify effector genes and mechanisms linking genetic risk to disease.

medRxiv · Jun 24, 2025 · PreprintGenetic & Genomic Medicine

Tissue-specific and circulatory immune signatures of mucosal inflammation in Crohn's disease

Lucia Ramirez-Navarro, Gareth‐Rhys Jones, Tobi Alegbe, Bradley T. Harris, Michelle Strickland, Mennatallah Ghouraba, Jasmin Ostermayer, Noor Wana, Xueqi Hu, Jason Skelton, Wendy Garri, Biljana Brezina, Charry Queen Caballes, Steven R. Leonard, Vivek Iyer, , Tim Raine

This study uses single-cell RNA sequencing to analyze immune cell transcriptional profiles in mucosal and circulatory compartments of Crohn's disease patients, revealing tissue-specific inflammation signatures and identifying circulating T cells with mucosal-like features.

medRxiv · Jun 3, 2025 · PreprintGenetic & Genomic Medicine