Repetitive head impacts induce neuronal loss and neuroinflammation in young athletes
Morgane L M D Butler, Nida Pervaiz, Kerry Breen, Samantha M. Calderazzo, Petra Ypsilantis, Yichen Wang, Julia Cammasola Breda, Sarah A. Mazzilli, Raymond Nicks, Elizabeth Spurlock, Marco M. Hefti, Kimberly L. Fiock, Bertrand R. Huber, Victor E. Alvarez, Thor D. Stein, , Jonathan D. Cherry
This study shows that repetitive head impacts in young athletes cause neuronal loss and neuroinflammation before CTE pathology, with specific cellular changes linked to disease progression.
bioRxiv · Mar 26, 2024 · PreprintNeuroscience