Cell type-resolved proteomics reveals intra- and intercellular signalingin Alzheimers disease
Xue Zhang, Kaiwen Yu, Him K. Shrestha, Ying Zhou, Jiyuan Yang, Zhen Wang, Xiaokang Ren, Ping-Chung Chen, Huan Sun, Danting Liu, Yun Jiao, Jay M. Yarbro, Ju Wang, Zhiping Wu, Kiara Harper, , Junmin Peng
The paper presents a cell type-resolved proteomic atlas of Alzheimer's disease mouse models, identifying thousands of cell-specific protein changes and highlighting astrocyte-microglia signaling.
bioRxiv · Feb 4, 2026 · PreprintNeuroscience