Author

Kim Heilemann

Center for Regenerative Therapies Dresden

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 3 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Organism:zebrafish· 4 Approach:statistical model· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:scRNA-seq· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1

Frequent Co-Authors

Catherina Gwynne BeckeriD· 4 shared Alberto Docampo-SearaiD· 3 shared Anja Bretschneider· 3 shared Daniela ZölleriD· 2 shared Friederike KesseliD· 2 shared Markus Westphal· 2 shared Mehmet İlyas CoşacakiD· 2 shared Thomas BeckeriD· 2 shared

Activity by Year

2024-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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4 shared papersNeuroscience

Catherina Gwynne BeckerORCID

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4 papers

Recent·Most cited

Baseline regulatory programs in larval and adult neural progenitors converge towards an injury-induced state after spinal cord injury

Mehmet İlyas Coşacak, Dmitrii Severinov, Markus Westphal, Kim Heilemann, Denise Baerhold, Anja Bretschneider, Susanne Reinhardt, Juliana G. Roscito, Thomas Becker, Catherina Gwynne Becker, Anna R. Poetsch

The paper compares regulatory changes in larval and adult zebrafish spinal progenitors after injury, showing they converge to a lesion-reactive state with distinct gene expression patterns.

bioRxiv · Aug 10, 2026 · PreprintBioinformatics

Diverse origins and transcriptional profiles of macrophages in a spinal lesion in zebrafish

Kim Heilemann, Elena Vanessa Jidav, Oezge Cark, Stephen J. Enos, Bastian Wolf, Catherina Gwynne Becker, Thomas Becker, Alberto Docampo-Seara

The paper identifies heterogeneous and dynamic gene expression in macrophage subpopulations during zebrafish spinal cord regeneration.

bioRxiv · Jun 30, 2026 · PreprintNeuroscience

A reparative neutrophil subpopulation promotes spinal cord regeneration in zebrafish by controlling macrophage inflammation via Il-4

Xiaobo Tian, Alberto Docampo-Seara, Kim Heilemann, Friederike Kessel, Daniela Zöller, Anja Bretschneider, Thomas Becker, Catherina Gwynne Becker

The paper shows that a neutrophil subpopulation expressing il4 promotes spinal cord regeneration in zebrafish by reducing Il-1β in macrophages/microglia, and this effect can be rescued by il4 overexpression or Il-1β reduction.

bioRxiv · Feb 26, 2026 · PreprintNeuroscience

Microglia attenuate regenerative neurogenesis via sema4ab after spinal cord injury in zebrafish

Alberto Docampo-Seara, Mehmet İlyas Coşacak, Kim Heilemann, Friederike Kessel, Ana‐Maria Oprişoreanu, Markus Westphal, Özge Çark, Daniela Zöller, Josi Arnold, Anja Bretschneider, Alisa Hnatiuk, Nikolay Ninov, Catherina Gwynne Becker, Thomas Becker

This study shows that sema4ab in microglia suppresses regenerative neurogenesis after spinal cord injury in zebrafish by altering microglia activation and fibroblast cytokine expression.

bioRxiv · Oct 16, 2024 · PreprintNeuroscience