Thomas Becker

This study shows that sema4ab in microglia suppresses regenerative neurogenesis after spinal cord injury in zebrafish by altering microglia activation and fibroblast cytokine expression.

This study shows that C9ORF72 deficiency in zebrafish causes retinal degeneration, including reduced thickness, gliosis, and neuronal loss, but not spinal cord pathology.

The paper uses synthetic CRISPR gRNAs and in vivo pre-screening to identify pro-regenerative genes in spinal cord injury, finding that tgfb1a promotes regeneration by controlling inflammation.