Suppression of p53 response by targeting p53-Mediator binding with a stapled peptide
Benjamin L. Allen, Kim Quach, Taylor Jones, Cecilia Blair Levandowski, Christopher C. Ebmeier, Jonathan D. Rubin, Timothy Read, Robin D. Dowell, Alanna Schepartz, Dylan J. Taatjes
The paper develops a stapled peptide that inhibits p53-Mediator interaction, suppressing p53 transcriptional activity in cancer cells.
Cell Reports · Apr 1, 2022Peer-reviewedMolecular Biology