Author

Tanaka K. Remba

Koch Institute for Integrative Cancer Research At MITORCID 0000-0001-9531-4341Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Darrell J. IrvineiD· 2 shared Jonathan DyeiD· 2 shared Yizhou DongiD· 2 shared Yuebao ZhangiD· 2 shared Amir LedbetteriD· 1 shared Ashley A. LemniosiD· 1 shared Bridget Li· 1 shared Byungji KimiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersBioengineering

Darrell J. IrvineORCID

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2 papers

Recent·Most cited

BioengineeringbioRxivPreprintJun 8, 2025

Engineering gene expression dynamics via self-amplifying RNA with drug-responsive non-structural proteins

Parisa Yousefpour, Justin R. Gregory, Kristen Si…·Darrell J. Irvine

This paper designs a drug-regulated gene expression system using self-amplifying RNA with TMP-responsive degradation domains, showing enhanced immune responses in mice.

7 citations

mouseexperimental assay

𝕏 PostBluesky

BioengineeringbioRxivPreprintMar 9, 2025

Targeted suppression of type 1 interferon signaling during RNA delivery enhances vaccine-elicited immunity

Byungji Kim, Ryan Ramsey Hosn, Tanaka K. Remba…·Darrell J. Irvine

This study shows that co-delivering siRNA targeting IFNAR1 with RNA vaccines enhances antigen expression, immune cell infiltration, and antibody and T cell responses.

5 citations

mousebulk RNA-seq

𝕏 PostBluesky