Kwantae Kim

Validated CRISPR/Cas9 guide RNAs targeting neurodevelopmental genes in the tunicate Ciona robusta

The paper validates CRISPR/Cas9 guide RNAs for eight neurodevelopmental genes in Ciona robusta, showing varying mutagenesis efficacy and improved correlation with RS3 scores.

A gene regulatory network for specification and morphogenesis of a Mauthner Cell homolog in non-vertebrate chordates

The paper identifies a gene regulatory network downstream of Pax3/7 in tunicate Ciona robusta ddNs, showing distinct transcription factors regulate different developmental branches.

Evolution of a chordate-specific mechanism for myoblast fusion

The paper investigates the evolutionary origins of myoblast fusion mechanisms in chordates, identifying the emergence of Myomaker and Myomixer and their roles in muscle development across species.

Neuron subtype-specific effector gene expression in the Motor Ganglion of Ciona

The paper compares transcriptomes of two neuron subtypes in Ciona's Motor Ganglion to identify subtype-specific effector genes involved in morphogenesis and differentiation.

Neurogenin regulates effectors of migratory neuron cell behaviors in Ciona

The paper identifies candidate genes regulated by Neurogenin in Ciona's bipolar tail neurons, suggesting conserved roles in neuronal migration and development.