Xiang Niu

The paper investigates the evolutionary origins of myoblast fusion mechanisms in chordates, identifying the emergence of Myomaker and Myomixer and their roles in muscle development across species.

This paper introduces SPOTS, a method for integrating spatial transcriptome and proteome data, and shows it reveals biological processes in spleen and breast cancer samples.

This study identifies R47H-TREM2 mutation-induced proinflammatory microglial states in human AD and tauopathy mice, showing Akt pathway involvement and potential therapeutic targets.

This study uses single-cell genomics in Ciona to map cardiopharyngeal fate decisions, revealing FGF-MAPK signaling's role in maintaining multipotency and the Tbx1/10-Dach pathway's role in suppressing the first heart lineage program.